Obesity is one factor which makes a person susceptible to diabetes mellitus. Even so, when already exposed to diabetes the weight of the patient will certainly drop dramatically.
Diabetes is indeed often not realized by the sufferer. Usually, someone realized there was disruption because he looked thin and his weight is down though not to go on a diet.
When we eat, the blood sugar levels will rise. Normally, this blood sugar enters the cell for energy metabolism. But, in patients with diabetes mellitus, blood sugar remained circulating in the blood circulation so that cells will starve.
Metformin is one of the drugs commonly prescribed for the treatment of type 2 diabetes. It works to reduce high blood sugar levels in obese diabetics.
How Metformin Can Reduce Weight
Metformin reduces blood sugar levels by inhibiting the production of glucose from the liver and by increasing the sensitivity of cells to insulin (a hormone that lowers blood sugar levels). In addition, some patients who took this drug experienced weight loss.
One explanation that may be related to this is a loss of appetite due to reduced insulin production. One study showed that diabetic patients taking metformin consumed fewer calories and then lost weight.
Metformin effect on weight loss can be increased when combined with low-carbohydrate diet and regular exercise. According to another study, women who are overweight and at risk of developing diabetes are able to lose weight with metformin when combined with low-calorie food intake and low-carbohydrate diets.
Side Effects of Metformin
Metformin can be taken safely by diabetic patients, to control blood glucose without significant reduction, at blood sugar levels. In addition, it can prevent weight gain or even lead to weight loss. The use of metformin to reduce non-diabetic weight has not been confirmed. Consult your doctor before taking metformin.
Common side effects of metformin include:
- Decreased appetite
These side effects often cause people to stop taking metformin. These side effects can be avoided by taking the extended-release form of this drug which slows the release in the gastrointestinal tract thereby reducing the symptoms.
Less common side effects include allergic reactions, which can lead to trouble breathing and swallowing, chest pain, swelling of the throat, or dizziness. Immediately contact emergency services or medical consultation if any of these occur.
Another rare side effect is lactic acidosis which usually occurs in people with liver disease, heart attack, lung, or kidney disease. Symptoms may include a sudden drop in blood pressure rapid breathing, stomach pain, vomiting, confusion, fainting, or extreme weakness. Immediately contact emergency services and hospitalization may be required.
Long-term use of metformin can lead to vitamin B12 deficiency which can affect the function of nerves and red blood cells. Careful monitoring of vitamin B12 in the blood so it must be done before and during treatment.